Scientific publications

Sobrin L, Seddon JM. 2014. Nature and nurture – genes and environment – predict onset and progression of macular degeneration. Progr Retinal Eye Res, 40: 1-15.

Macular Degeneration (AMD) and Diabetic Retinopathy (DR): World Drug Market 2013– 2023. (2012).

Fritsche LG, Chen W, Schu M et al. 2013. Seven new loci associated with age-related macular degeneration. Nat Genet, 45(4): 433-439 (

MATA et al, 2013 Visual Cycle Modulation: A Novel Therapeutic Approach For Treatment of GA In Dry AMD, Retinal Physician (

Awh CC et al. 2013. CFH and ARMS2 Genetic Polymorphisms Predict Response to Antioxidants and Zinc in Patients with Age-related Macular Degeneration. Ophtalmology 120:2317-2323 (

Tokarz P, Kaarniranta K, Blasiak J. 2013. Role of antioxidant enzymes and small molecular weight antioxidants in the pathogenesis of age-related macular degeneration (AMD). Biogerontology 14: 461- 482. (

Priya RR, Chew EY, Swaroop A. 2012. Genetic studies of age-related macular degeneration: lessons, challenges and opportunities for disease management. Ophthalmology, 119(12): 2526-2536. (

Fritsche LG, Fleckenstein M, Fiebig BS, et al. 2012. A subgroup of age-related macular degeneration is associated with mono-allelic sequence variants in the ABCA4 gene. IOVS, 53: 2112- 2118. (

Cruz-Jentoft AJ, Baryens JP, Bauer JM, Boirie Y, Cederholm T, Landi F, Martin FC, Michel JP, Rolland Y, Schneider SM, Topinková E, Vandewoulde M, Zamboni M. 2010. Sarcopenia : European consensus on definition and diagnosis. Report of the European Working Group on Sarcopenia in Older People. Age Ageing, 39(4): 412-423. (

Herzlich AA, Tuo J, Chan CC. 2008. Peroxisome proliferator-activated receptor and age- related macular degeneration. PPAR Research, article ID 389507. (

Maeda A, Maeda T, Golczak M, Palczewski K. 2008. Retinopathy in mice induced by disrupted all-trans-retinal clearance. J Biol Chem, 283: 26684-26693. (

Gehrs KM et al. 2006. Age-related macular degeneration: emerging pathogenetic and therapeutic concepts. Ann Med., 38:450-471 (

Marques-Vidal P, Ruidavets JB, Cambou JP, Ferrières J. 2003. Changes and determinants in cigarette smoking prevalence in southwester France, 1985-1997. Eur J Public Health, 13: 168-170. (

Thompson DA,Gal A. 2003. Vitamin A metabolism in the retinal pigment epithelium: genes, mutations, and diseases. Progr Retinal Eye Res, 22: 683-703.

Hyman L, Neborsky R. 2002. Risk factors for age-related macular degeneration : an update. Curr Opin Ophthalmol, 13(3): 171-175. (

AREDS report N°8, 2001. A Randomized, Placebo-Controlled, Clinical Trial of High-Dose Supplementation With Vitamins C and E, Beta Carotene, and Zinc for Age-Related Macular Degeneration and Vision Loss. Arch Ophthalmol., 119:1417-1436

Smith W, Assink J, Klein R, Mitchell P, Klaver CC, Klein BE, Hofman A, Jensen S, Wang JJ, de Jong PT. 2001. Risk factors for age-related macular degeneration : Poold findings from three continents. Ophthalmology, 108(4): 697 704. (

Marmorstein AD. 2001. The polarity of the retinal pigment epithelium. Traffic, 2(12): 867-872. (

Sparrow JR, Nakanishi K, Parish CA. 2000. The lipofuscin fluorophore A2E mediates blue-light- induced damage to retinal pigmented epithelial cells. IOVS, 41: 1981-1989. (

Scott IU, Smoddy WE, Schiffman J, Feuer WJ, Pappas CJ. 1999. Quality of lire of low-vision patients and the impact of low-vision services. Am J Ophthalmol, 128(1): 54-62.

Williams RA, Brody BL, Thomas RG, Kaplan RM, Brown SI. 1998. The psychological impact of macular degeneration. Arch Ophthalmol, 116: 514-520.

Klein R, Klein BEK, Jensen SC, Meuer SM, 1997. The five-year incidence and progression of age- related maculopathy : the Beaver Dam Eye Study. Ophthalmology, 104(1): 7-21.

Moisseiev J, Alhalel A, Masuri R, Treister G. 1995. The impact of the macular photocoagulation study results on the treatment of exudative age-related macular degeneration. Arch Ophthalmol, 113(2): 185-189. (

Marmor MF. 1990. Control of subretinal fluid: experimental and clinical studies. Eye (Lond), 4(Pt 2): 340-344. (

Feeney-Burns L, Eldred GE. 1983. The fate of the phagosome: conversion to ‘age pigment’ and impact in human retinal pigment epithelium. Trans Ophthalmol Soc UK, 103: 416-421.

Harman D. 1981. The aging process. Proc Natl Acad Sci U.S.A., 78(11): 7124-7128. (