SEPTEMBER 29, 2021

Biophytis to Present Full Results from the SARA-INT Phase 2b Trial of Sarconeos (BIO101) in Sarcopenia at the 11th annual International Conference on Frailty and Sarcopenia Research (ICFSR) September 29 u2013 October 2, 2021

Biophytis today announces it will present full results from the SARA-INT Phase 2 trial of Sarconeos (BIO101) in Sarcopenia at the International Congress on Frailty and Sarcopenia Research (ICFSR) to be held virtually from September 29 to October 02, 2021

ICFSR is the key international scientific event on Frailty and Sarcopenia and is attended by leading researchers, physicians and Biotech/Pharma in this field.

The results of SARA-INT, with efficacy endpoints including subgroup analysis and secondary endpoints, will be presented by Cendrine Tourette PhD in a dedicated seminar on Thursday, September 30 at 9:00-9:30 AM EST. The seminar will be followed by a Q&A session with Biophytis representatives: Cendrine Tourette, PhD (SARA Project Leader), Jean Mariani, MD, PhD (Board Director) and Waly Dioh, PhD (Chief Operating Officer). The Q&A session will be moderated by Roger A. Fielding, PhD, Principal Investigator of the SARA-INT trial and who heads the Nutrition, Exercise Physiology & Sarcopenia team at Tufts University in Boston.

Biophytis has previously announced the top-line results of the SARA-INT study. Data showed that Sarconeos (BIO101) at the highest dose (350 mg bid) demonstrated a clinically meaningful improvement in the 400-meter walk test (400MWT), the primary endpoint of the study. Sarconeos (BIO101) showed a very good safety profile at the doses of 175 mg bid and of 350 mg bid. Based on the SARA-INT results, Biophytis is now preparing the phase 3 program and associated regulatory agency interactions.