Press Releases 2023

Biophytis announces receipt of Nasdaq Notice Biophytis announced that it has received written notification (the “Notification Letter”) from the Nasdaq Stock Market LLC (“Nasdaq”) dated April 24, 2023, indicating that, based on the reported stockholders’ equity of (€1,911,000) of Biophytis as reported in its 20-F, the Company does not meet the minimum shareholders’ equity criteria of $2,500,000 in stockholders’ equity for continued listing (the “Nasdaq Letter”). The Notification Letter has no immediate effect on the listing of the ADSs, and they will continue to trade on The Nasdaq Global Select Market under the symbol “BPTS”. Under Nasdaq Listing Rule 5550(b)(1),

Biophytis regains compliance with NASDAQ minimum bid price requirement Biophytis announced that it has received written notification (the “Notification Letter”) from the Nasdaq Stock Market LLC (“NASDAQ”) dated April 14, 2022, indicating that Biophytis has regained compliance with the Nasdaq Global Select Market minimum bid price requirement. On October 20, 2022, the Nasdaq had notified Biophytis that based upon a closing bid price of less than $1.00 per share for the Company’s American Depositary Shares (“ADSs”) for the prior 30 consecutive business deay period, the Company no longer satisfied Nasdaq Listing Rule 5550(a)(2). Since then Nasdaq has determined that for

Biophytis Announces 2022 Financial Results and 2023 Perspectives €11.1M of available cash and equivalents on December 31, 2022, and financing instruments for a total of €22M allowing financial visibility beyond mid 2024 Positive results of the Phase 2-3 COVA study for the treatment of severe COVID-19 with Sarconeos (BIO101) Early Access Program (EAP) submission in France by June 2023 while preparing filing for conditional marketing authorization in the USA and Europe for Sarconeos (BIO101) in COVID-19 Fullscreen Mode

The Combined General Meeting will be held on second call on April 17, 2023 Fullscreen Mode

Biophytis presented Sarconeos (BIO101) as a possible treatment candidate for long COVID after hospitalization during the 13th annual International Conference on Frailty and Sarcopenia Research (ICFSR) Fullscreen Mode

Biophytis to Present Sarconeos’ (BIO101) Development as a Drug Candidate in Rare Neuromuscular Diseases at the Muscular Dystrophy Association (MDA) Clinical & Scientific Conference Fullscreen Mode

Biophytis announces ratio change under its American Depositary Receipt (“ADR”) program Fullscreen Mode

Positive results from the Phase 2-3 COVA study presented at the 21st ERS 2023 Lung Science Conference .Biophytis announced that it presents the positive results of the phase 2-3 COVA study with Sarconeos (BIO101) in severe COVID-19 at the European Respiratory Society 2023 21st Lung Science Conference taking place in Estoril, Portugal, between the 9th and the 12th of March 2023. Professor Suzana Lobo, MD – Hospital de Base Da Faculdade de Medicina de São José Do Rio Preto, São Paulo, Brazil and Investigator of the COVA study in Brazil, will be holding an oral presentation of the results titled

Biophytis announces the signature of a master service agreement with Intsel Chimos, a pharmaceutical company that will operate Sarconeos (BIO101) in France for the treatment of severe forms of COVID-19 Biophytis and Intsel Chimos signed a master service agreement under which Intsel Chimos will be the operating pharmaceutical company/exploitant, partner and distributor in France for the drug Sarconeos (BIO101) developed by Biophytis in the context of the early access program application. The application request for early access program, currently underway with the Haute Autorité de Santé (the French National Authority for Health, HAS), aims to allow treatment with Sarconeos (BIO101)